A New Link between γδ T Cells and Myeloid Cells in Malaria?
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چکیده
منابع مشابه
Regulatory T Cells and Myeloid-Derived Suppressor Cells in Patients with Peptic Ulcer and Gastric Cancer
Background: Regulatory T Cells (Tregs) and Myeloid-Derived Suppressor Cells (MDSCs) are two main regulatory cells modulating the immune responses in inflammation and cancer. Objective: To investigate and compare Tregs and MDSCs in peptic ulcer and gastric cancer. Methods: Patients with dyspepsia were selected and divided into three groups of non-ulcer dyspepsia (NUD, n=22), peptic ulcer disease...
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A current major challenge of acute myeloid leukemia research is to develop immunotherapeutic strategies that would be employable in all patients. We recently reported that appropriately stimulated γδ T cells are fully capable of mediating cytotoxicity against leukemic blasts.
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Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of myeloid cells that play a major role in the regulation of immune responses in many pathological conditions. These cells have a common myeloid origin, relatively immature state, common genetic and biochemical profiles, and, most importantly, the ability to inhibit immune responses. Although initial studies of MDSCs were almost...
متن کاملregulatory t cells and myeloid-derived suppressor cells in patients with peptic ulcer and gastric cancer
background: regulatory t cells (tregs) and myeloid-derived suppressor cells (mdscs) are two main regulatory cells modulating the immune responses in inflammation and cancer. objective: to investigate and compare tregs and mdscs in peptic ulcer and gastric cancer. methods: patients with dyspepsia were selected and divided into three groups of non-ulcer dyspepsia (nud, n=22), peptic ulcer disease...
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γδ T cells are one of the three immune cell types that express antigen receptors. They contribute to lymphoid antitumor surveillance and bridge the gap between innate and adaptive immunity. γδ T cells have the capacity of secreting abundant cytokines and exerting potent cytotoxicity against a wide range of cancer cells. γδ T cells exhibit important roles in immune-surveillance and immune defens...
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ژورنال
عنوان ژورنال: Immunity
سال: 2018
ISSN: 1074-7613
DOI: 10.1016/j.immuni.2018.02.003